Faculty & Research
Individual research laboratories typically have a substantial collection of supplies and equipment, including spectroscopic and structural analysis tools. Increasingly, however, modern research in Chemistry requires access to expensive state-of-the-art equipment, making it necessary to purchase such items on a shared basis and to provide staff for operation and maintenance. Facilities to pursue research in emerging areas of Chemistry are present in the Chemistry Building and are accessible to all graduate students:
Located in the Chemistry building, the Max T. Rogers NMR Facility provides twelve high-field Varian/Agilent NMR spectrometers with proton resonance frequencies ranging from 300 – 600 MHz. This includes four 300 MHz instruments for routine studies, three 400 MHz NMR spectrometers for solid-state experiments, two 500 MHz spectrometers for routine and advanced experiments, two fully automated 500 MHz spectrometers equipped each with 96 sample robotic autosamplers, and a 600 MHz instrument for biomolecular and advanced small molecule work.
In 2020, the NMR facility will undergo room renovations and extensive upgrades to the research instruments. These will include a new 500 MHz spectrometer with an X-nucleus optimized cryoprobe and a reaction monitoring accessory, a new 600 MHz system with HCN cryoprobe, a new 800 MHz system with cryoprobe and fast-MAS solid-state NMR capabilities, and two new 400 MHz solid-state NMR systems optimized for bio-solids.
Since mass spectrometry is an indispensable tool in many research areas, Department researchers have easy access to twelve mass spectrometers at the MSU Mass Spectrometry and Metabolomics Core, located in the adjacent Biochemistry Building. The Core offers a variety of GC/MS, LC/MS/MS, and MALDI mass spectrometers with an assortment of inlets and ionization methods, and functions as an open access laboratory. Students are encouraged to become trained instrument users; training includes discussions of theory and operation of Core instruments; following training, users enjoy 24/7 access using a Google Calendar reservation system. Recent Chemistry researchers have used these instruments for low- and high-resolution (accurate mass) analyses of synthetic compounds, quantitative analyses, and compound localization using mass spectrometry imaging. Facility staff are available to provide expert consultation regarding method development and data interpretation, and perform sample analyses upon request. Mass spectrometers can also be found in many individual research laboratories.
The Chemistry Department X-ray Facility was just awarded (2019) an MRI-NSF grant for a dual microfocus source with a HYPIX Detector, which allows for rapid non-shutter operation. This gives us the latest technology for single crystal structural analysis. The University continues to provide access to the APS Synchrotron through LSCAT for protein crystallography and other X-ray diffraction needs. The department also houses a routine powder X-ray diffractometer and an X-ray fluorescence spectrometer for qualitative and semi-quantitative analyses. Graduate students may request hands-on training in the use of these instruments, which allows for them to gain valuable experience and expertise in X-ray technologies.
In addition to these major instrument facilities in the Department, conveniently-located instrument rooms house liquid and gas chromatographic equipment, UV-VIS, FTIR, FT-MS, and fluorescence and Raman spectrometers. Elemental analysis via x-ray fluorescence, AA, and ICP are also available in the Chemistry Building.
The Chemistry Department operates well-equipped shops for the design and fabrication of unique and custom instrumentation and apparatus, and the repair of existing equipment required for research and teaching. The Machine Shop and the Glassblowing Facility are staffed by experienced professionals who are a vital component of the research performed at MSU. If you need something but can’t buy it anywhere, it can likely be constructed with facilities in our Department.