Current Research Support
NIH R01 AG066223-01A1 (PI, Tepe) 09/15/19-05/31/23
Title: Small molecule induced proteolytic destruction of intrinsically disordered proteins
NIH-IGNITE 1R61NS111347-01A1 (PI, Tepe) 12/01/19-11/31/22
Title: Development of cellular HTS for 20S proteasome enhancers
NIH R21 AG061306-01 (PI, Tepe) 12/01/19-11/31/21
Title: Multiparameter optimization of new phenothiazines for proteasome activation
International Myeloma Foundation (PI, Tepe) 01/01/19-12/31/19
Title: Targeting c-Myc degradation to treat myeloma
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Thank you Taylor, Sophie and Allison of all your hard work in helping me put this together and for the data needed to get his funded!
Rahman was selected as one of the five faculty members from Pakistan's leading research intensive university, LUMS, to receive this award. Rahman is currently an Associate Professor at LUMS after getting his PhD from the Tepe lab at MSU in 2011.
Congrats from all of us!
Biomedicines 2022, 10, 938. https://doi.org/10.3390/biomedicines10050938
Title: Small molecule 20S proteasome enhancer regulates MYC protein stability and exhibits antitumor activity in multiple myeloma.
Journal of Medicine Chemistry 2022, in print.
Title: "Design, Synthesis and Biological Evaluation of Potent 20S Proteasome Activators for the Potential Treatment of α-synucleinopathies"