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Daniel Colombani-Garay

Daniel was born and raised in Puerto Rico. He attended George Mason University in Fairfax, VA where he graduated with a B.S. in Chemistry and minored in Neuroscience. During the Summer of 2019, he conducted research at University of Massachusetts Medical School under supervision of Dr. Gang Han synthesizing amphiphilic nanoparticles for in-situ drug delivery. For his senior year project, he worked under supervision of Dr. Mikell Paige on the synthesis of substituted pyrazolopyridine heterocycles for inhibition of superoxide dismutase.

In the Tepe Lab, Daniel is working on the design, synthesis, and evaluation of small molecule activators of the 20S proteasome to induce proteolytic destruction of intrinsically disordered proteins. Outside of lab, Daniel enjoys cooking, reading, and hanging out with his dog, Rocko.


Lin, W, Colombani‚ÄźGaray, D, Huang, L, Duan, C, Han, G. Tailoring nanoparticles based on boron dipyrromethene for cancer imaging and therapy. WIREs Nanomed Nanobiotechnol. 2020; 12:e1627. https://doi.org/10.1002/wnan.1627

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Latest News

May 23, 2022 Very grateful for the NIH's continued support of our work and the funding of our new grant!

Thank you Taylor, Sophie and Allison of all your hard work in helping me put this together and for the data needed to get his funded!

May 22, 2022 Congrats to Rahman Saleem, who was awarded the Vice Chancellors Award for Teaching Excellence at LUMS!

Rahman was selected as one of the five faculty members from Pakistan's leading research intensive university, LUMS, to receive this award. Rahman is currently an Associate Professor at LUMS after getting his PhD from the Tepe lab at MSU in 2011.

Congrats from all of us!

April 19, 2022 Congrats Evert and Allison on your new publication in Biomedicine! Great work.

 Biomedicines 2022, 10, 938. https://doi.org/10.3390/biomedicines10050938

Title: Small molecule 20S proteasome enhancer regulates MYC protein stability and exhibits antitumor activity in multiple myeloma.

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