Novel Applications of Ultrafast Laser Spectroscopy
Adjunct Professor (Physics)
Primary Research Area
Other Area(s) of Interest
Chemical Physics (CP)
(Research Description PDF)
Ultrafast lasers, with pulse durations shorter than 10–13 s — less time than it takes for atoms to move — have already led to Nobel Prizes in Chemistry and Physics. These lasers are ideal for probing and controlling chemical reactions. Our group has three wellfunded thrust areas of scientific leadership: (a) Understanding and controlling chemistry under intense laser field radiation: Exploring molecular dynamics at energies ranging from 1015 to 1020 W/cm2. (b) Biomedical imaging and sensing: Label free biomedical imaging and explosives detection. (c) Development of novel spectroscopic approaches: New laser sources, pulse shapers, and computers will revolutionize how we study chemical reactions. Progress in or research programs requires fundamental advances in science, often questioning established dogmas and accomplishing what others have determined to be impossible.
Understanding and controlling chemistry under intense laser field radiation - High intensity laser light has provided notable advances across a broad range of disciplines including physics, chemistry, medicine, and defense. Our common understanding of light-matter interactions fails at extreme intensities, especially when the field strength of the incident radiation is strong enough to deform the Coulomb potential of the atom and liberate electrons. At intense enough fields those electrons become relativistic, opening up an abundance of novel atomic and molecular processes to investigate. In our lab, we take advantage of laser sources and pulse shaping methods we have developed to understand and to control the dynamics of exotic chemical reactions in gas, liquids, and solids induced by strong laser fields. Our recent projects include study of exotic chemical reactions, such as the formation of H3 +, to explore unlikely chemical processes involving dissociation and formation of multiple chemical bonds, occurring under the influence of strong laser fields.
In addition, we explore relativistic pulse compression to achieve high efficiency conversion of femtosecond pulses into attosecond pulses.
Biomedical Imaging and Sensing - Whether the goal is to diagnose and treat retinal diseases or detect oral cancer, the challenge is perfecting chemically resolved imaging. Our group has been pioneering laser technology for unstained biomedical imaging. In both areas, developments from our group are a combination of fundamental scientific advances with source development. We routinely collaborate with a number of medical centers nationally as well as other research groups on MSU’s campus.
Development of novel spectroscopic approaches - Our group has revolutionized how ultrashort pulses are measured and compressed (technology patented, commercialized, and used around the world). The fundamental science behind this breakthrough technology is based on coherent control of quantum mechanical process. The technology is known as Multiphoton Intrapulse Interference Phase Scan, and it has allowed the generation of intense (0.5 mJ) sub-two cycle pulses (2008), as well as record performance from ultrafast fiber lasers. Our work on source development includes nonlinear optics studies in particular self-action processes (when the pulse modifies the material and the material modifies the pulse).
Mechanisms and time-resolved dynamics for trihydrogen cation (H3 +) formation from organic molecules in strong laser fields, N. Ekanayake, M. Nairat, B. Kaderiya, P. Feizollah, B. Jochim, T. Severt, B. Berry, K. Raju P., K.D. Carnes, S. Pathak, D. Rolles, A. Rudenko, I. Ben-Itzhak, C.A. Mancuso, B.S. Fales, J.E. Jackson, B.G. Levine, and M. Dantus, Sci. Rep. 2017, 7, 4703.
Time-resolved signatures across the intramolecular response in substituted cyanine dyes, M. Nairat, M. Webb; M.P. Esch, V.V. Lozovoy, B.G. Levine and M. Dantus, Phys. Chem. Chem. Phys. 2017, 19, 14085-14095.
Eye-safe near-infrared trace explosives detection and imaging, G. Rasskazov, A. Ryabtsev, and M. Dantus, Opt. Express 2017, 25, 5832-5840.
Femtosecond real-time probing of reactions MMXVII: The predissociation of sodium iodide in the A 0+ state, G. Rasskazov, M. Nairat, I. Magoulas, V.V. Lozovoy, P. Piecuch, and M. Dantus, Chem. Phys. Lett. 2017, in press.
Multiphoton excited hemoglobin fluorescence and third harmonic generation for non-invasive microscopy of stored blood, I. Saytashev, R. Glenn, G.A. Murashova, S. Osseiran, D. Spence, C.L. Evans, And M. Dantus, Biomed. Opt. Express 2016, 7, 3449-3460.
Stain-free histopathology by programmable supercontinuum pulses, H. Tu, Y. Liu, D. Turchinovich, M. Marjanovic, J.K. Lyngsø, J. Lægsgaard, E.J. Chaney, Y. Zhao, S. You, W.L. Wilson, B. Xu, M. Dantus and S.A. Boppart, Nat. Photonics 2016, 10, 534-540.
University Distinguished Professor 2015
MSU Foundation Professor 2015
B.A. & M.A., 1985, Brandeis Univ.
Ph.D., 1991, California Institute of Technology
Postdoctoral Research Fellow, 1991-1993, California Institute of Technology.
|2016||University Distinguished Professor in Chemistry and Physics||Michigan State University|
|2016||MSU Foundation Professor||Michigan State University|
|2015||Fellow of the American Physical Society|
|2014||Elected Fellow of the Optical Society of America|
|2014||Elected Fellow of the National Academy of Inventors|
|2013||MSU Innovator of the Year award|
|2010||Science and Technology Awards from Corp! magazine||Biophotonic Solutions|
|2008||Distinguished Faculty Award|
|2001||Featured in article||ACS 125th Anniversary Issue of Chemical and Engineering News|
|1998||Alfred P. Sloan Fellowship||Alfred P. Sloan Foundation|
|1998||Teacher-Scholar Award||Camille and Henry Dreyfus Foundation|
|1996||Eli Lilly Teaching Fellowship||Michigan State University|
|1995||Packard Fellowship for Science and Engineering||The David and Lucile Packard Foundation|
|1995||Beckman Young Investigator Award||Beckman Foundation|
|1994||General Electric Foundation Faculty Award||General Electric|
|1993||New Faculty Award||Camille and Henry Dreyfus Foundation|
|1992||Nobel Laureate Signature award for Graduate Education in Chemistry||American Chemical Society|
|1991||Ph.D.||California Institute of Technology|
|1991 - 1993||Postdoctoral Research Fellow||California Institute of Technology|
|1991||Milton and Francis Clauser Doctoral Prize||California Institute of Technology|
|1991||The Herbert Newby McCoy Award||California Institute of Technology|
|1985||Melvin M. Snider Prize in Chemistry||Brandeis University, Waltham, MA|
|1985||Earl C. Anthony Fellowship||California Institute of Technology|
|1985||Bachelor of Arts Magna Cum Laude||Brandeis University, Waltham, MA|
|1985||Phi Beta Kappa||Phi Beta Kappa (Brandeis University, Waltham, MA)|
|1985||M.A.||Brandeis University, Waltham, MA|
|1985||Bachelor of Arts||Brandeis University, Waltham, MA|