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Greg Swain

Electrochemistry, Carbon Material Science, Corrosion and Neuroanalytical Chemistry

Greg Swain Greg Swain

Professor & Member of the Neuroscience Program

314 CEM

517-353-1090


REU Site Director


Research webpage


Research Area

Analytical (An)

Area(s) of Interest

Biological (Bi)

Material (Ma)

Research

(Research Description PDF)

Research in our group is interdisciplinary and spans several fields: physical and analytical electrochemistry, carbon material science, point-of-care medical diagnostics, neuroanalytical chemistry, and corrosion of additively manufactured metal alloys. We conduct fundamental research to address key problems and technological needs in health and the environment. Our core science lies in the preparation, processing and application of multiple carbon materials including conducting diamond films and powders, nitrogenincorporated tetrahedral amorphous carbon films, and screen- and inkjet-printed carbons.

Electrochemical Reaction Kinetics and Mechanisms
Electrochemical Reaction Kinetics and Mechanisms

Electrochemical Reaction Kinetics and Mechanisms – Factors controlling electrontransfer kinetics and mechanisms of soluble redox systems at boron-doped diamond and nitrogen-incorporated tetrahedral amorphous carbon thin-film electrodes are being investigated in aqueous, organic, and ionic liquid electrolytes. We seek to learn how factors such as the surface chemistry, electrode microstructure and doping level affect electrochemical reaction rate constants and mechanisms.

Point-of-Care Medical Diagnostics
Point-of-Care Medical Diagnostics

– The use of an electrochemical sensing platform for multiple potentially relevant biomarkers in collected exhaled breath condensate is a new paradigm in respiratory disease treatment and management. Modified screen- and inkjetprinted carbon electrodes are being used in diagnostic technology for the monitoring and care of patients with lung cancer, pneumonitis, COPD, obliterative bronchiolitis, cystic fibrosis, and general respiratory tract infections, which all are characterized by oxidative and nitrosative stress. Key inflammatory markers targeted are pH, hydrogen peroxide, nitric oxide, and peroxynitrite.

We are also working on similar diagnostic technology for electrochemically monitoring biomarkers of wound healing and infection.

Neuroanalytical Chemistry
Neuroanalytical Chemistry

– In vitro electrochemical methods, immunohistochemistry and other analytical tools are being used in collaborative research to better understand how potential changes in neuromuscular signaling in the gastrointestinal tract are associated with pathological conditions in animal models of obesity and neurodegenerative disease. Molecules, such as serotonin, nitric oxide, ATP and acetylcholine, are being detected with diamond microelectrodes and microelectrode sensors.

Additively Manufactured Metal Alloys and Coating Systems for Corrosion Control
Additively Manufactured Metal Alloys and Coating Systems for Corrosion Control

Additively Manufactured Metal Alloys and Coating Systems for Corrosion Control – Additive manufacturing (AM), or 3D printing, is the process of fabricating objects layer-by-layer, as opposed to traditional subtractive manufacturing technologies. We seek to understand how the surface texture, alloy microstructure and elemental composition affect the electrochemical behavior of AM aluminum, steel, and titanium alloys prepared by laser powder-based sintering and fused filament fabrication methods. It is also of interest to learn how surface pretreatments and coating systems mitigate corrosion on these alloys. Electrochemical methods, various microscopies and surface science tools are routinely used in these studies.

Selected Publications

Effect of Laser Cleaning and Hyperpassivation on the Electrochemical Behavior of Aluminum Alloys, McFall- Boegeman S; Yancey D. O'Neill T; Davidson N; Swain GM., J. Electrochem. Soc. 2021, 168, 031501.

Local and Long-Range Organization in Room Temperature Ionic Liquids, Wang Y; Parvis F; Hossain MdI; Ma K; Jarošová R; Swain GM; Blanchard GJ., Langmuir 2021, 37, 605-615.

An Electrochemical ATP Biosensor with Enzymes Entrapped within a PEDOT Film, Peteu SF; Russell SA; Galligan JJ; Swain GM., Electroanal. 2021, 33, 495-505.

Temperature Dependence of the Heterogeneous Electron-Transfer Rate Constant and Diffusion Coefficient for Ferrocene Carboxylic Acid in Room Temperature Ionic Liquids at Various Carbon Electrodes, Jarošová R; Bhardwaj K; Swain GM., J. Electroanal. Chem. 2020, 167, 114744.

Inkjet-Printed Carbon Nanotube Electrodes for Measuring Pyocyanin and Uric Acid in a Wound Fluid Simulant and Culture Media, Jarošová R.; McClure SE.; Gajda M.; Jovic M.; Girault HH.; Lesch A.; Maiden M.; Waters C.; Swain GM., Anal. Chem. 2019, 91, 8835-8844.

CV

Editor-in Chief, Diamond and Related Materials (Elsevier), 2011-present

Member of the Neuroscience Program and The Fraunhofer Center for Coatings and Laser Applications (CCL)

Adjunct Appointments: Departments of Chemical Engineering and Materials Science, and Pharmacology and Toxicology

B.A., 1985, Univ. of Texas at Dallas

Ph.D., 1991, Univ. of Kansas

Postdoctoral Research Fellow, 1991-92, Space Power Institute and the Department of Chemical Engineering, Auburn Univ.

JSPS Postdoc¬toral Research Fellow, 1992-93, Tohoku Univ., Japan

Full CV (PDF)

Awards/Honors

2018 Outstanding Faculty Award College of Natural Science
2015 Corrosion Best Paper Award
1992 - 1993 JSPS Postdoctoral Research Fellow Tohoku University, Japan
1991 Ph.D. University of Kansas
1991 - 1992 Postdoctoral Research Fellow Space Power Institute and the Department of Chemical Engineering, Auburn University
1985 Bachelor of Arts University of Texas at Dallas
Associate Editor Diamond and Related Materials