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Department of Chemistry Michigan State University |
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Brush-Modified Membranes for Protein Purification Multilayered Polyelectrolyte Membranes Membrane-Based Antibody Arrays On-probe Capture of Phospho-peptides for Mass Spectrometry |
Who are
we? We're a research group in the
chemistry
department at Michigan State University
led by Dr.
Merlin Bruening. The group currently consists (summer 2006) of nine graduate
students, two undergraduate students, and two postdoctoral associates.
What do we do? We develop new thin films for protein purification in porous supports, membrane-based water reclamation, purification for MALDI mass spectrometry, and selective catalysis. In some cases, students spend a month or two in France or Ukraine in collaborative research. What tools do we use? We use surface infrared spectroscopy, field-emission scanning electron microscopy, electrochemistry, mass spectrometry, ellipsometry, nanofiltration, and atomic force microscopy. Whenever possible we try to exploit characterization techniques that don't require ultrahigh vacuum so we can simulate actual conditions. More Information? Click on any of
the links above for other graphics and descriptions. If you are interested
in graduate work in chemistry at Michigan State University,
click
here. We also have a list of
publications describing prior work. If you have specific questions, send e-mail to bruening@chemistry.msu.edu
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The Bruening group (summer 2006): From left to right, front:
Malaisamy Ramamoorthy, Jinhua Dai, Srividhya Kidambi, Parul Jain, Somnath Bhattacharjee, Fei Xu, and Lu Ouyang. Not pictured: Elizabeth Igrisen.
back: Lei Sun, David Dotzauer, Jamie Dunn, Randy Benedict, Maneesha Adusumilli, and Merlin Bruening.
Schematic diagram of analytes approaching a multilayer polyelectrolyte
membrane. Multilayer membranes can separate monovalent and divalent anions
(Cl-/SO42- selectivities as high as 1000) as
well as small organic molecules such as glucose and sucrose. In some
cases, we have also separated gases such as O2 and N2.
Because the membranes are ultrathin, they allow high fluxes. |